. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Genes Chromosomes Cancer. 2009 Sep;48(9):806–815. doi: 10.1002/gcc.20685

TABLE 5.

Rearrangements detected in peripheral blood of breast cancer patients undergoing treatment

Patient	Draw	Site	Chromosome	Partner location (bp	MLL microhomology partner
2002	1st	6807	14	67141929	GTCTGTTGTGAGCCCTTGAGCCCAGGAATTTGAAGTTATAG
2002	1 month	6771	1	70342304	TATCTTCCCATGTTCTTAAATGTGTTCAGTTTCTTATA
2002	1 month	5735	9	139711966	GGTTGATTATGTTTTTCTACAAGAATAAAAACTACTTTG
2003	1 month	6805	19	59007420	TGTATTGCCAAGTCTGTTGTGAGCCACTGCACTTAGCCC
2005	1st	7023	11	117863937	TGGGAAAAAATCTACTAAAAATACAAAAAATTAGCCAGGTGTGG
2010	1 month	6805	22	23673419	TGCCAAGTCTGTTGTGAGCCACCGCGCCTGGCCTGGT

Draw refers to the time of blood collection after treatment was initiated. Most individuals exhibited more than one rearrangement per sample. Site is breakpoint location within MLL BCR (see Figure 2) Translocation breakpoint highlights region of microhomology (bold). Partner location (breakpoint site) identified by BLAST using build 36.3 and refers to individual chromosome numbering in base pairs.