Table 4. Factors Associated with Physicians’ Having Ever Referred a Patient for Genetic Testing.
| Ever Referred to Genetics Center or Counselor |
Ever Referred to Specialist |
Ever Referred to a Clinical Trial |
Ever Referred to Any Site of Care |
Ever Ordered or Ever Referred |
|
|---|---|---|---|---|---|
| N=943 | N=941 | N=934 | N=945 | N=945 | |
| OR (95% CI) | |||||
| CHARACTERISTICS OF PHYSICIANS’ PATIENT PANELS | |||||
| High Proportion Minority Patients |
0.73 (0.45-1.18) |
0.63 (0.40-1.00) |
0.46 (0.22- 0.96)* |
0.60 (0.36-0.99)* |
0.61 (0.35-1.07) |
| High Proportion Medicaid Patients |
0.58 (0.37-0.92)* |
0.64 (0.41-1.01) |
1.04 (0.58-1.89) |
0.49 (0.30-0.80)** |
0.60 (0.35-1.05) |
| High Proportion Patients with Primary Language other than English |
1.02 (0.65-1.60) |
0.76 (0.50-1.18) |
0.78 (0.42-1.45) |
0.87 (0.54-1.40) |
0.91 (0.54-1.55) |
| High Proportion Uninsured Patients |
0.84 (0.56-1.27) |
1.04 (0.70-1.54) |
1.28 (0.75-2.19) |
0.86 (0.55-1.34) |
0.82 (0.51-1.32) |
| OTHER PRACTICE CHARACTERTICS | |||||
| Size of Practice 1-2 Doctors |
0.68 (0.48-0.96)* |
0.77 (0.54-1.08) |
1.01 (0.65-1.57) |
0.65 (0.44-0.97)* |
0.63 (0.40-1.00) |
| ≥ 2 Doctors | REF | REF | REF | REF | REF |
| Region Northeast |
2.17 (1.39-3.39)† |
1.26 (0.82-1.93) |
1.05 (0.61-1.82) |
1.68 (1.03-2.74)* |
2.00 (1.16-3.45)* |
| Midwest | 1.72 (1.15-2.59)** | 1.10 (0.74-1.64) | 1.27 (0.76-2.13) | 1.55 (0.97-2.47) | 1.45 (0.85-2.46) |
| West | 1.29 (0.83-2.00) | 0.90 (0.59-1.38) | 1.61 (0.92-2.82) | 1.18 (0.73-1.92) | 1.22 (0.70-2.13) |
| South | REF | REF | REF | REF | REF |
| PHYSICIAN CHARACTERISTICS | |||||
| Age < 45 |
REF | REF | REF | REF | REF |
| 45-64 | 0.62 (0.43-0.88)** | 0.73 (0.52-1.01) | 0.97 (0.65-1.45) | 0.57 (0.38-0.85)** | 0.78 (0.50-1.21) |
| ≥ 65 | 0.23 (0.14-0.40)† | 0.35 (0.20-0.59)† | 0.56 (0.26-1.17) | 0.27 (0.15-0.48)† | 0.29 (0.16-0.54)† |
| Self-Identified Race Black |
1.38 (0.45-4.21) |
1.64 (0.61-4.42) |
0.71 (0.13-3.92) |
1.77 (0.52-6.00) |
3.66 (0.64-20.94) |
| Hispanic | 0.77 (0.30-1.93) | 1.70 (0.73-3.93) | 1.55 (0.58-4.16) | 1.32 (0.49-3.59) | 0.82 (0.30-2.25) |
| Asian | 0.57 (0.37-0.89)* | 1.04 (0.67-1.61) | 0.84 (0.46-1.53) | 0.79 (0.48-1.28) | 0.88 (0.53-1.49) |
| Other Race | 0.36 (0.15-0.88)* | 1.48 (0.57-3.82) | 0.86 (0.24-3.06) | 1.09 (0.38-3.09) | 0.92 (0.30-2.84) |
| White | REF | REF | REF | REF | REF |
| Specialty Family Practice |
3.29 (2.40-4.51)† |
1.38 (1.02-1.86)* |
0.85 (0.57-1.26) |
2.56 (1.81-3.61)† |
2.15 (1.44-3.20)† |
| Internal Medicine | REF | REF | REF | REF | REF |
| Full-time Faculty Appointment |
1.60 (0.98-2.62) |
1.17 (0.73-1.88) |
3.14 (1.76-5.60)† |
1.66 (0.97-2.82) |
0.95 (0.53-1.72) |
| PHYSICIAN CHARACTERISTICS RELATED TO GENETICS | |||||
| Received Training in Clinical Genetics in Medical School |
1.13 (0.82-1.58) |
1.56 (1.14-2.13)** |
1.01 (0.66-1.55) |
1.35 (0.94-1.92) |
1.55 (1.04-2.32)* |
| Received Training in Clinical Genetics in CME |
1.53 (1.11-2.10)** |
2.31 (1.70-3.12)† |
2.36 (1.58-3.53)† |
2.21 (1.56-3.13)† |
2.41 (1.61-3.60)† |
| Accurate Knowledge of Current Legal Protections |
2.45 (1.31-4.58)** |
1.94 (1.10-3.41)* |
2.20 (1.30-3.72)** |
6.13 (2.21-16.99) † |
9.75 (2.32-40.97)** |
| Confident Interpreting Genetic Test Results |
0.89 (0.41-1.90) |
0.64 (0.29-1.43) |
0.85 (0.36-2.00) |
1.12 (0.44-2.84) |
0.72 (0.24-2.13) |
| Feels Prepared to Counsel Patients Considering a Genetic Test |
1.31 (0.58-2.93) |
2.39 (0.98-5.84) |
1.50 (0.65-3.47) |
2.43 (0.76-7.74) |
2.41 (0.59-9.77) |
| Early Adopter of New Diagnostic Tests |
1.51 (0.97-2.33) |
1.20 (0.77-1.87) |
1.18 (0.70-1.98) |
1.27 (0.76-2.13) |
2.66 (1.34-5.25)** |
| Optimistic that Genetics Will Improve Treatment |
1.08 (0.67-1.73) |
1.11 (0.70-1.76) |
0.78 (0.41-1.48) |
0.99 (0.59-1.65) |
0.88 (0.50-1.53) |
Note: Also included in model but not shown: practice setting (independent practice versus those practicing in a health maintenance organization, hospital-based practice, community health center or other setting).
p<0.05
p<0.01
p<0.001
Only those respondents for whom there were complete data were included in each regression analysis, with available cases for individual regressions ranging from 934 (83% of full sample) to 945 (84% of full sample) respondents.