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. Author manuscript; available in PMC: 2009 Oct 20.
Published in final edited form as: J Lipid Res. 2006 Jun 21;47(9):2028–2041. doi: 10.1194/jlr.M600177-JLR200

Fig. 2.

Fig. 2

Role of peroxisome proliferator-activated receptor α (PPARα) in the control of hepatic elongase and desaturase expression. Homozygous wild-type (+/+) and PPARα-null (−/−) mice on a Sv/129 genetic background (19, 20) were fed either a control diet or one containing WY14643 (50 or 500 mg/kg diet; Bioserv, Piscataway, NJ) for 1 week. Liver RNA was extracted and used as a template for qRT-PCR. Results are reported as fold change in mRNA abundance (transcript/cyclophilin) for each enzyme (means ± SD; n = 4). * P ≤ 0.05 by Student’s t-test versus the wild type (+/+) on a control diet.