Inhibition of HGF-Induced Scattering Response of A549 Cells by siRNA Knockdown of the Met Receptor
(A) Reduction in cellular Met receptor levels following incubation with siRNA oligos directed against the Met receptor.
(B) A549 cells treated with vehicle (Oligofectamine, left panels) or Met siRNA (right panels) and stimulated with 50 ng/ml hepatocyte growth factor (HGF) for 12 hr. Cells were fixed and stained with crystal violet (top panels) or DAPI (bottom panels). Scale bars represent 100 μm.