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. 2009 Sep 14;27(29):4821–4826. doi: 10.1200/JCO.2009.22.3032

Table 1.

Pathogenesis: Virchow's Triad

Stasis Bed rest and immobility, extrinsic compression of vessel by mass
Blood components Tumors and macrophages produce procoagulants, inflammatory cytokines
Vessel damage Direct tumor invasion, indwelling catheters, chemotherapy, erythropoietin, antiangiogenic agents