Figure 3 Rate of cognitive deterioration in patients with autopsy-confirmed pure DLB, pure AD, or AD+DLB

Analysis of last 4 Mini-Mental State Examination (MMSE) scores before death of persons from the University of Kentucky Alzheimer's Disease Center autopsy series with pathologically confirmed pure dementia with Lewy bodies (DLB; n = 9), pure Alzheimer disease (AD; n = 107), or AD+DLB (n = 27) was performed to determine how the average intercept and slope varied among the 3 neuropathologic diagnostic groups after adjusting for years of education. With the caveat that it is a small group, the pure DLB group had higher MMSE scores 4 visits before death compared to the other groups and declined less perceptibly than the AD+DLB group (see text for details).