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. 2009 Sep 1;37(18):6184–6193. doi: 10.1093/nar/gkp600

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© The Author(s) 2009. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Accuracy of structure prediction. Fraction of correctly predicted helices (green bars) compared with the mammalian 16S rRNA consensus models (36). (A) RNAsalsa significantly outperforms MXSCARNA and RNAalifold (default parameter settings; three-sample test for equality of proportions without continuity correction; χ² = 19.96, df = 2, P < 0.0001). Average tree-edit distance (37) (B) between predicted individual structures and the mammalian 16S rRNA reference model. RNAsalsa predictions conform the consensus model much better (paired sampled t-test; t = 33.46, df = 1, P < 0.0001; N = 26).