FIG. 2.
Low-producer phenotype is consistent over time. (A) HIV-1 core antigen production in three different replicate cultures from three separate CD4+ T cell infection experiments with HIV-1JR-CSF (MOI 0.003) is shown, with data from different replicates within each experiment clustered together. (B) Infection kinetics curves for six low-producer individuals and four individuals having normal capacity for productive in vitro infection with HIV-1JR-CSF (MOI 0.003). A solid line indicates low producers; a dashed line indicates normally susceptible. For HIV-1 low producers, lines represent the log-transformed mean of results from three separate experiments involving cells isolated from different venipuncture dates. SEM are shown.