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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Gastroenterology. 2009 Jun 26;137(4):1403–1414. doi: 10.1053/j.gastro.2009.06.049

Figure 2. Inflammatory cytokines are upregulated in colons of FoxO4 KO mice.

Figure 2

(A) qRT-PCR analysis of RNA transcripts from colonic mucosa of untreated, vehicle, and TNBS treated WT and Foxo4 KO mice (n=4 ± SEM, *, p < 0.05). Transcript levels are expressed relative to an internal control (GAPDH). (B) Relative mRNA of CCL5, CCL9, TNFα, and IFNγ from intestinal epithelial cells and (C) from epithelial-minus mucosal cell fraction (n=4 ± SEM, *, p<0.05). After normalizing to an internal control (GAPDH), the transcript level in WT was set to 1 and levels in KO were expressed as relative to WT.