Figure 1. IL-10 differentiates monocytes into CD209+CD163+ MΦ.
(A) Human peripheral monocytes were harvested at 0 h or stimulated for 48 h with IL-10, IL-15, or media and labeled with specific antibodies. Results shown as mean ± SEM (n ≥ 4). **p < 0.001 versus media (t = 48 h).
(B) IL-10 and IL-15 derived MΦ were double-labeled with antibodies against CD209 and specific markers. Results represent mean ± SEM (n ≥ 4) percent of CD209+ cells positive for indicated antibody. ‡p < 0.05 **p < 0.001 versus IL-15 derived MΦ.