Table 1.

Antibody Array analysis of changes in cytokine levels in mesangial cells following exposure to DL-homocysteine (50 μM).

Cytokine	Change	P-value
TIMP-1	1.9	0.02
TNFα	1.1	NS
β-NGF	1.1	NS
MIP-3α	1	NS
MCP-1	1.2	NS
IL-6	1.1	NS
IL-10	1.1	NS
CINC-2 (MIP-2)	2.4	0.01
IFN-γ	0.5	0.045
Fractalkine	0.2	0.02
GM-CSF	0.4	0.048
LIX	0.9	NS

Values are expression relative to levels in cells cultured in glucose (5.6 mM) with 100 μM L-cysteine but lacking homocysteine; n = 3. Abbreviations: TIMP-1 - tissue inhibitor of metalloproteinases 1; TNFα- tumor necrosis factor alpha; β-NGF - beta nerve growth factor, MIP-3α- macrophage inflammatory protein 3 alpha; MCP-1 - monocyte chemotactic protein 1; IL-6 - interleukin 6; IL-10 - interleukin 10; CINC-2 - cytokine-induced neutrophil chemoattractant 2 (also known as macrophage inflammatory protein 2 and GROβ [growth-regulated gene product beta]); IFN-γ - interferon beta; GM-CSF - granulocyte monocyte colony stimulating factor; LIX - Lipopolysaccharide (LPS)-induced chemokine.