Table 3.
Dose, Gy | Stage, weeks | Mutation rate per offspring band
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Total* | Ratio† | P-value‡ | Paternal§ | Ratio† | P-value‡ | Maternal§ | Ratio† | P-value‡ | ||
0 | — | 0.0123 | — | — | 0.0556 | — | — | 0.0463 | — | — |
0.5 | 6 | 0.0193 | 1.56 | 0.1711 | 0.1333 | 2.40 | 0.0995 | 0.0667 | 1.44 | 0.7510 |
0.5 | 10 | 0.0248 | 2.01 | 0.0129 | 0.1455 | 2.62 | 0.0457 | 0.0545 | 1.18 | 0.9999 |
0.5 | 6 + 10 | 0.0223 | 1.81 | 0.0198 | 0.1400 | 2.52 | 0.0325 | 0.0600 | 1.30 | 0.8280 |
1 | 3 | 0.0113 | 0.91 | 0.8930 | 0.0806 | 1.45 | 0.6267 | 0.0323 | 0.70 | 0.8285 |
1 | 6 | 0.0274 | 2.22 | 0.0015 | 0.2192 | 3.94 | 0.0003 | 0.0548 | 1.18 | 0.9978 |
1 | 10 | 0.0280 | 2.27 | 0.0134 | 0.2400 | 4.32 | 0.0026 | 0.0600 | 1.30 | 0.9831 |
1 | 6 + 10 | 0.0276 | 2.23 | 0.0008 | 0.2245 | 4.04 | 0.0001 | 0.0561 | 1.21 | 0.9404 |
Total mutation rate was estimated as the number of independent mutations scored in each animal per minisatellite band, assuming 30 bands per offspring.
Ratio exposed to control.
Probability of difference from the control group (Fisher’s exact test, two-tailed; statistically significant values are in bold).
Number of paternal and maternal mutations scored by two single-locus probes, Ms6-hm and Hm-2.