Table 3.

Association of SNPs with CAD in basic and full models among the Young Affected (n=552 vs. n=773 Controls; minor allele frequencies are provided in Table 2).

		Basic Model*		Full Model†
GENE	SNP name	OR‡ (95% CI)	p-value	OR‡ (95% CI)	p-value
CDGAP	rs10934490	1.05 (0.89, 1.24)	0.59	1.06 (0.88, 1.27)	0.55
MYLK	rs16834817	1.18 (0.92, 1.51)	0.21	1.13 (0.86, 1.48)	0.38
KALRN	rs6810298	1.09 (0.91, 1.30)	0.36	1.12 (0.92, 1.36)	0.25
	rs9289231	0.97 (0.72, 1.30)	0.83	0.95 (0.69, 1.31)	0.75
	rs12637456	1.03 (0.85, 1.24)	0.80	1.09 (0.89, 1.35)	0.41
	rs1444768	1.04 (0.88, 1.23)	0.64	1.08 (0.90, 1.29)	0.40
	rs1444754	0.93 (0.79, 1.10)	0.41	0.99 (0.82, 1.19)	0.88
	rs4234218	0.87 (0.74, 1.04)	0.12	0.89 (0.74, 1.07)	0.20
GATA2	rs2335052	0.89 (0.70, 1.12)	0.31	0.90 (0.70, 1.16)	0.42
	rs3803	1.07 (0.88, 1.32)	0.50	1.03 (0.83, 1.29)	0.78
	rs2713604	1.11 (0.93, 1.33)	0.25	1.21 (0.99, 1.46)	0.057

^*Basic model adjusted for sex only;

^†Full model adjusted for sex, BMI, diabetes, hypertension, hyperlipidemia, and smoking;

^‡All odds ratios are per additional variant allele under the additive genetic model.