The sequences of the putative amide synthetases are shown in comparison with human NAT1 (P50295) and NAT from Mycobacterium smegmatis (086309). The essential residues as indicated are after [61]. The amide synthetases listed are as follows: O52547|RIFF_AMYMD 3-amino-5-hydroxybenzoic acid synthase - Amycolatopsis mediterranei (Nocardia mediterranei)., A8M6D1|A8M6D1_9ACTO N-acetyltransferase - Salinispora arenicola , Q2PC63|Q2PC63_STRAH Putative amide synthase - Streptomyces achromogenes subsp. Rubradiris, Q84G21|Q84G21_STRHY GdmF - Streptomyces hygroscopicus, Q1L0S9|Q1L0S9_STRHY GelD - Streptomyces hygroscopicus subsp. Duamyceticus, A8LFZ8|A8LFZ8_9ACTO N-acetyltransferase - Frankia sp. EAN1pec., A4FDM9|A4FDM9_SACEN 3-amino-5-hydroxybenzoic acid synthase - Saccharopolyspora erythraea (strain NRRL 23338), Q8KUF7|Q8KUF7_ACTPA Amide synthase - Actinosynnema pretiosum subsp. auranticum., Q848C2|Q848C2_STRHY Amide synthase - Streptomyces hygroscopicus (sequence cropped @ N-term to remove cloning artifacts)., Q0PLZ9|Q0PLZ9_9ACTO Putative N-acetyltransferase - Kitasatospora putterlickiae., Q8GNN3|Q8GNN3_STRHY ShnN - Streptomyces hygroscopicus., Q1L0S3|Q1L0S3_STRHY NapF - Streptomyces hygroscopicus subsp. duamyceticus.