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. 2009 Oct 1;106(42):17693–17698. doi: 10.1073/pnas.0909373106

Fig. 5.

Fig. 5.

Binding promiscuity of Nup145C. (A) Surface rendition of the Sec13·Nup145C nucleoporin pair derived from the Sec13·Nup145C hetero-octamer (Nup145C·Nup145C homo-dimerization) and the Sec13·Nup145C·Nup84 NTD heterotrimer (Nup145C·Nup84 NTD hetero-dimerization). The Nup145C homo-dimerization and hetero-dimerization surfaces are colored in green and yellow, respectively. The Sec13 and the remaining Nup145C surfaces are colored in orange and blue, respectively. (B) 90°-rotated views of the Sec13·Nup145C pair colored according to panel A (top), to a multispecies sequence alignment, ranging from 60% similarity (white) to 100% identity (red) (26) (middle), and to the electrostatic potential, from −10 kBT/e (red) to +10 kBT/e (blue). The orientation of all surface representations is identical in each column. As a reference, black lines encircle the Nup145C homo-dimerization and Nup84-interaction surfaces.