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. 2009 Oct 5;106(42):17876–17881. doi: 10.1073/pnas.0909357106

Fig. 3.

Fig. 3.

GATA-3 gene occupancy in Th2 cells. (A) Examples of GATA-3 ChIP signals in Th2 cells. The plots show unprocessed enrichment ratios for all probes within a genomic region (ChIP vs. whole genomic DNA). D-16 antibody ChIP dark blue, HG3–31 antibody ChIP light blue. (B) Composite GATA-3 enrichment profile in Th2 cells for genes that show significant binding within 4 kb from their transcription start site. D-16 ChIP dark blue, HG3–31 ChIP light blue. (C) Examples of genes with functions in Th1 cells that are bound by both T-bet and GATA-3. The plots show unprocessed enrichment ratios for all probes within a genomic region (ChIP vs. whole genomic DNA) for T-bet in Th1 cells (green) and GATA-3 (D16 ChIP) in Th2 cells (blue). (D) Examples of genes with functions in Th2 cells that are bound by both T-bet and GATA-3. Details as for C.