Table 1.
Relative repair activities for uracil-DNA and THF-DNA in Pol β null and Pol β-comp cells.
Cell type | Relative repair activitya for uracil-DNA (%) | Relative repair activitya for THF-DNA (%) |
---|---|---|
Pol β null | 85 ± 3.1 (P = 0.003)b | 82 ± 4.7 (P = 0.011)b |
Pol β-comp | 101 ± 5.0 (P = 0.82)b | 129 ± 5.8 (P = 0.005)b |
The relative repair activity was calculated by dividing the ratio (positive control vs. experimental) of luciferase activity for uracil-DNA or THF-DNA in Pol β null cells or Pol β-comp cells by the ratio in wild type cells. Values represent the mean ± SEM of 7 independent experiments, with three replicate cultures in each, at the 10 h time point after the beginning of the repair incubation.
P-value in student t-test was calculated by the comparison with wild type cells.