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. Author manuscript; available in PMC: 2010 May 27.

Published in final edited form as: J Med Chem. 2009 May 28;52(10):3397–3407. doi: 10.1021/jm900126v

Table 4.

NOE data of the Z- and E-isomers 14b and 15b (DMSO-d₆, 300 MHz)


Compound	H_irr	δ	H_obs	δ	%NOE
14b	H₈	8.01	5’-OH	4.84	0.17
	H₈	8.01	6’-OH	4.64	0.18
	H₈	8.01	H_6’(H_5’)	3.51	2.33
	H₈	8.01	H_4’	2.05–2.09	1.62
	5’-OH_’	4.84	H₈	8.01	0.71
	6’-OH	4.64	H₈	8.01	4.33
	H_5’(H_6’)	3.51	H₈	8.01	5.05
	H_5’(H_6’)	3.25–3.31	H₈	8.01	5.84
	H_4’	2.05–2.09	H₈	8.01	3.45
	H_3’	1.30–1.38	H_1’	7.09	1.41
	H_1’	7.09	H_3’	1.30–1.38	1.65
15b	H₈	8.04	H_3’	1.64	1.07
	H₈	8.04	H_3’	1.35–1.40	0.82
	6’-OH	4.63	H_1’	7.17	2.05
	H_5’(H_6’)	3..37–3.46	H_1’	7.17	1.27
	H_5’(H_6’)	2.97–3.03	H_1’	7.17	2.62
	H_4’	1.72–1.77	H_1’	7.17	0.74
	H_3’	1.64	H₈	8.04	1.48
	H_3’	1.30–1.38	H₈	8.04	2.30