FIG. 2.

Loss of tyrp1:eGFP from mosaic adults after treatment with 750 nM NCP. (A) 0 day. (B) 1 day. The arrow indicates one melanocyte that fully retained eGFP after treatment. The arrowhead indicates one melanocyte that partially retained eGFP after treatment. The eGFP no longer surrounds the melanin, and is not in dendritic processes (compare with the arrow). The double arrowhead indicates a melanocyte that lost all eGFP expression (compare with arrow and arrowhead). The asterisk indicates melanocytes that were initially negative for eGFP. The black carats mark the boundary of the myotome, which has mild autofluorescence. (C) Quantification of eGFP⁺ melanocytes in eight mosaic fish before and after NCP treatment. Scale bars are 200 μm.