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. 2009 Jul 21;39(2):100–108. doi: 10.1152/physiolgenomics.90354.2008

Table 1.

Gene Ontology list of significantly overrepresented gene categories by Z-score

Ontology List Array Z-Score
Biological Process
Cell adhesion 24 564 5.26
Focal adhesion formation 2 10 4.68
Cell-cell adhesion 10 181 4.3
Transmembrane receptor protein tyrosine kinase signaling pathway 9 158 4.19
Limb morphogenesis 4 42 4.14
Tissue development 12 251 4.13
Antiapoptosis 8 144 3.86
Male sex differentiation 3 29 3.79
Cell migration 9 192 3.49
Actin cytoskeleton organization and biogenesis 8 164 3.42
Calcium-independent cell-cell adhesion 2 17 3.37
Blood vessel development 7 141 3.25
Cell-matrix adhesion 4 63 3.05
Molecular Function
Extracellular matrix structural constituent 7 77 5.28
Myosin binding 2 11 4.4
Oxidoreductase activity 3 23 4.39
Structural molecule activity 20 551 3.93
Cytokine activity 9 187 3.55
Rab GTPase binding 2 16 3.49
Receptor signaling protein activity 7 131 3.45
Protein binding 95 4,681 3.23
Calcium ion binding 20 652 3.11
Transcriptional repressor activity 8 180 3.08
Cell Component
Collagen type VI 2 2 11.24
Collagen type I 2 3 9.1
Extracellular matrix 16 230 6.69
Anchoring collagen 2 8 5.35
Extracellular space 16 424 3.77
Apical junction complex 4 51 3.63
Cell-cell adherens junction 2 17 3.4
Intercellular junction 6 109 3.34
Plasma membrane part 36 1,398 3.32
Adherens junction 3 37 3.22