. 2009 Oct 1;106(41):17383–17388. doi: 10.1073/pnas.0907455106

Table 1.

Comparison of kinetic ΔG with equilibrium ΔG and β-Tanford values

CTPRan	ΔG_0→j^H₂O (kcal mol⁻¹)^*	ΔG_I-U^H₂O (kcal mol⁻¹)^†	ΔG_I-N^H₂O (kcal mol⁻¹)^‡	ΔG_U-N^H₂O (kcal mol⁻¹)^§	β_T TS1	β_T Intermediate	β_T TS2
2	3.3 ± 0.9	-	-	2.8 ± 0.4	0.56	-	-
3	6.1 ± 1.2	4.0 ± 1.5	5.1 ± 1.5	9.1 ± 2.1	0.35	0.49	0.58
4	9.0 ± 1.5	3.8 ± 1.4	5.9 ± 1.7	9.8 ± 2.2	0.37	0.47	0.49
5	11.8 ± 1.9	4.2 ± 1.2	6.4 ± 2.4	10.6 ± 2.7	0.30	0.45	0.46
6	14.7 ± 2.2	4.3 ± 0.6	10.7 ± 2.5	15.0 ± 2.6	0.24	0.34	0.36
8	20.4 ± 2.8	4.0 ± 0.3	14.6 ± 2.6	18.6 ± 2.6	0.16	0.25	0.26
10	26.1 ± 3.5	4.3 ± 0.4	17.8 ± 3.7	22.2 ± 3.7	0.15	0.23	0.23

All errors from kinetic data are obtained from propagation of errors obtained from the fitting of the data (shown in Table S3).

*Values averaged from the Ising fit of all equilibrium data and using Eq. 5 (SI Appendix); errors obtained from the propagation of a standard deviation of 3 averaged data sets (shown in Table S2).

^†Calculated from kinetic data using ΔG_U-1^H₂O = −RTln(k_IU^H₂O/k_UI^H₂O).

^‡Calculated from kinetic data using ΔG_I-N^H₂O = − RTln(k_NI^H₂O/k_IN^H₂O).

^§Calculated from kinetic data using ΔG_U-N^H₂O = − RTln(k_IU^H₂Ok_NI^H₂O/k_UI^H₂Ok_IN^H₂O). β_T values were obtained using Σ_xm_x/Σ_im_i, where Σ_xm_x is the sum of kinetic m-values between the unfolded state and state X on the reaction coordinate, and Σ_im_i is the sum of all kinetic m-values along the reaction coordinate.