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. Author manuscript; available in PMC: 2010 Jun 2.
Published in final edited form as: Circulation. 2009 May 18;119(21):2818–2828. doi: 10.1161/CIRCULATIONAHA.108.832915

Figure 2.

Figure 2

Substrate utilization in the hearts of WT and TG mice fed a HF or LF diet. (A and B) Relative contributions of each substrate to the oxidative metabolism in isolated mouse hearts perfused with 13C-labeled substrates during baseline (A) and high workload (B) (n=5 to 7 per group). (C-F) Myocardial oxygen consumption and oxygen efficiency for contractile function during baseline (C and E) and high workload (D and F) (n=3 to 4 per group). Total glycogen (G) and triglyceride (H) content (n=5 to 7 per group) in the hearts of WT and TG mice fed a HF or LF diet for 20 weeks. Data are mean ± SEM. *p < 0.05 vs LFWT; #p < 0.05 vs LFTG (see text for statistical significance for figure 2A and 2B).