Table 1.

Antiretroviral activities of IDV-NP-BMM

Days	7		14
Antibodies	Vim+	HIV-1p24+	Vim+	HIV-1p24+
MDM	368.88 ± 43.54	0	93.5 ±12.24	0
HIVE	419.11 ± 45.64	128.5 ± 31.35	103.17 ± 12.53	62 ± 5.02
HIVE and BMM-IDV-NP	342.26 ± 18.88	52.67 ± 20.12*	81.63 ± 19	22.88 ± 9.86*

Absolute numbers of Vim⁺ and HIV-1 p24⁺ MDM were determined from serial immunohistological sections. These were used to assess levels of HIV-1 infection. Mean (± SEM) are absolute numbers of Vim⁺ and HIV-1 p24⁺ MDM determined for 5 animals per group. IDV-NP-BMM intravenous administration significantly reduced levels of HIV-1p24⁺ MDM when compared to untreated HIVE mice. Uninfected MDM injected into the subcortex of immunodeficient mice served as a control.

^*p < 0.05 compared IDV-NP-BMM treated to untreated HIVE mice.