Figure 6.

H3K36me3 and H3K79me1 are found at exonic nucleosomes and have a higher signal at highly expressed exons. Heat maps of nucleosome (A), H3K36me3 (B), and H3K79me1 (C) signal patterns at individual human internal exons. Rows in the heat maps correspond to 2-kb windows centered on intron/exon junctions (I/E junctions) of internal exons in highly expressed genes. Only internal exons with lengths between 100 and 300 bp and with flanking introns with lengths of at least 100 bp are shown. Each window (row in the heat map) was split into subwindows of 100 bp and the average signal calculated. The exons (rows in the heat map) are ordered according to exon expression. The gray tones were assigned using the signal quantiles of considered windows for H3K36me3, H3K79me1, and nucleosome separately. The groups of high-, medium-, and low-expressed exons (Fig. 4) are indicated with black boxes.