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Cardiovascular responses to (A) IMD (1 nmol·kg−1) or (B) AM (3 nmol·kg−1) following administration of saline (0.4 mL·h−1) or AM22–52 (500 nmol·kg−1·h−1). Values are mean and vertical bars represent SEM, n= 6–8 per group. *P < 0.05 versus baseline (Friedman's test), #P < 0.05 for integrated (0–30 min) changes (Mann–Whitney U-test). AM, adrenomedullin; IMD, intermedin.
