Table 1.

Concentrations and actions of pharmacological tools used

Agent	Action	Final concentration
ODQ	Soluble guanylate cyclase inhibitor	10 µM
Indomethacin	Cyclooxygenase inhibitor	5 µM
CPTIO	Nitric oxide scavenger	1 mM
U-51605	Prostacyclin synthase inhibitor (PGISi)	10 µM
Raloxifene	Aldehyde oxidase inhibitor	50 nM
Oxypurinol	Xanthine oxidase inhibitor	100 µM
l-NMMA	eNOS inhibitor	300 µM

These represent final bath concentrations required or established for maximum effect on nitrite-induced vasodilatation.

ODQ, 1H [1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one; CPTIO, carboxy-2-phenyl-4,4,5,5-tetramethyl-imidazoline-1-oxyl-3-oxide; l-NMMA, l-N^G-monomethyl arginine.