Table 1.
Flow cytometric analysis of epidermal growth factor receptor expression of and reactivity of panitumumab with human carcinoma cell lines
| Tumour type | Cell line | Mean fluores cence intensity | % Positive cells |
|---|---|---|---|
| Breast | MCF-7 | 653.6 | 65.1 |
| MD-MBA-231 | 575.8 | 99.9 | |
| Colon | CBS | 56.4 | 97.5 |
| DLD-1 | 138.9 | 99.9 | |
| GEO | 64.9 | 99.1 | |
| HT-29 | 59.8 | 97.3 | |
| KM12SM | 78.9 | 95.6 | |
| LS-174T | 62.5 | 99.9 | |
| MIP | 167.3 | 98.9 | |
| Gastric | N87 | 46.1 | 97.8 |
| Lung | A549 | 59.4 | 99.5 |
| Melanoma | A-375 | 51.0 | 94.4 |
| M21 | 26.8 | 99.9 | |
| SK-MEL | 34.0 | 98.6 | |
| Ovarian | OVCAR-3 | 433.6 | 99.9 |
| SKOV-3 | 138.6 | 97.1 | |
| Pancreatic | BxPC3 | 191.8 | 99.9 |
| CFPAC-1 | 416.1 | 99.9 | |
| MiaPaCa-2 | 421.3 | 99.2 | |
| SHAW | 118.5 | 99.9 | |
| Prostate | 22Rv1 | 97.3 | 99.9 |
| DU145 | 330.2 | 99.9 | |
| LNCaP | 153.7 | 99.9 | |
| PC3 | 150.9 | 99.9 | |
| Renal | ACHN | 253.6 | 99.9 |
| Epidermoid | A431 | 2072.2 | 99.3 |
| Glioma | U-87 MG | 75.1 | 99.9 |