Figure 6.

Plasma thromboxane B₂ (TXB₂) levels in experimental groups. TXB₂ levels were higher (than sham) in the thromboangiitis obliterans (TAO) model rats and further increased on addition of exogenous urocortin (Ucn; see Methods). These effects of urocortin were prevented by treatment with NBI-27914 or astressin, but not by antisauvagine-30. Values are presented as means ± SEM (n= 8). *P < 0.05, versus sham operated group; #P < 0.05, versus TAO model group; †P < 0.05, versus urocortin group. N, normal; Sh, sham; TAO, TAO model; U, urocortin; U + NB, U + NBI-27914; U + A30, urocortin + antisauvagine-30; U + As, urocortin + astressin.