Table 2.

Mean percent blood glucose reduction in diabetic rats (N = 6)

Time (h)	Gliclazide	Efavirenz	Efavirenz + Gliclazide (Single dose treatment)	Efavirenz + Gliclazide (Multiple dose treatment)
1	32.92 ± 1.95	-04.55 ± 2.55	24.83 ± 1.98**	28.26 ± 1.62
2	42.05 ± 1.73	-05.08 ± 2.46	30.02 ± 1.59***	36.39 ± 1.89*
3	31.21 ± 1.74	-03.21 ± 2.41	20.70 ± 1.31***	25.45 ± 1.93*
4	25.13 ± 1.77	-02.40 ± 2.24	16.78 ± 2.21***	20.78 ± 1.36*
6	36.14 ± 1.56	03.99 ± 1.97	22.15 ± 1.34***	30.12 ± 1.47*
8	44.05 ± 1.55	04.45 ± 2.26	32.01 ± 1.39***	38.27 ± 1.42*
10	28.56 ± 1.87	05.39 ± 1.72	16.25 ± 2.25***	20.89 ± 1.49**
12	24.66 ± 2.32	04.28 ± 1.53	08.49 ± 2.32***	11.31 ± 2.17***

***Significant at P < 0.001 compared to gliclazide control

**Significant at P < 0.01 compared to gliclazide control

*Significant at P < 0.05 compared to gliclazide control