Table 5.
Mean percent blood glucose reduction in diabetic rats (N = 6)
|
Time (h) |
Gliclazide | Nevirapine | Nevirapine + Gliclazide*(Single dose treatment) | Nevirapine + Gliclazide*(Multiple dose treatment) |
| 1 | 33.45 ± 1.76 | 02.08 ± 0.38 | 32.42 ± 1.47 | 33.23 ± 1.63 |
| 2 | 42.50 ± 1.40 | 04.34 ± 1.40 | 41.68 ± 1.27 | 42.28 ± 1.32 |
| 3 | 31.87 ± 1.68 | 04.42 ± 1.62 | 30.69 ± 1.61 | 31.66 ± 1.66 |
| 4 | 25.88 ± 1.42 | 06.11 ± 1.61 | 25.43 ± 1.47 | 25.82 ± 1.34 |
| 6 | 36.89 ± 1.30 | 06.28 ± 1.53 | 36.25 ± 1.48 | 36.78 ± 1.38 |
| 8 | 44.46 ± 1.46 | 03.08 ± 0.54 | 43.25 ± 1.35 | 44.37 ± 1.33 |
| 10 | 28.72 ± 1.76 | 01.67 ± 0.67 | 27.93 ± 1.55 | 28.92 ± 1.68 |
| 12 | 24.39 ± 1.81 | 01.64 ± 0.71 | 23.81 ± 1.80 | 24.98 ± 1.83 |
*Statistically no significance compared to gliclazide control