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. Author manuscript; available in PMC: 2010 Apr 17.
Published in final edited form as: Immunity. 2009 Apr 9;30(4):566–575. doi: 10.1016/j.immuni.2009.02.006

Figure 2. Influenza virus-induced cytokine and chemokine production depends on cryopyrin, but not ipaf.

Figure 2

Groups (n=4) of B6 (WT), cryopyrin−/− (CRYO−/−) and ipaf−/− (IPAF−/−) mice were infected i.n with 4×103 EID50 of PR8 influenza virus and sampled 3d later to determine levels of IL-1β (A), IL-18 (B), TNF-α (C), IL-6 (D), IFN-γ (E), IL-12p40 (F), KC (G), and MIP-2 (H), in BAL fluid. Results are mean ± S.D. and are representative of three independent experiments. Data were analyzed with Student’s t-test (*, p<0.05).