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. Author manuscript; available in PMC: 2010 Apr 17.
Published in final edited form as: Immunity. 2009 Apr 9;30(4):566–575. doi: 10.1016/j.immuni.2009.02.006

Figure 3. Caspase-1 is required for influenza virus-induced secretion of cryopyrin-dependent cytokines and chemokines.

Figure 3

Groups of 4 B6 (WT) and caspase-1−/− (CASP1−/−) mice were infected i.n with 4×103 EID50 of PR8 influenza virus and levels of IL-1β (A), IL-18 (B), TNF-α (C), IL-6 (D), IFN-γ (E), IL-12p40 (F), KC (G), and MIP-2 (H) were measured in BAL fluid 3d later. Results are mean ± S.D.. Data were analyzed with Student’s t-test (*, p<0.05) and are representative of three independent experiments.