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. Author manuscript; available in PMC: 2010 Apr 22.
Published in final edited form as: J Am Chem Soc. 2009 Apr 22;131(15):5424–5431. doi: 10.1021/ja808704m

Figure 3.

Figure 3

The single block strategy toward EPO(78-113) glycopeptide fragment.a

a(a) Pseudoproline and Dmb dipeptides used to enhance the synthetic efficiency of the peptidic fragment of EPO(78-113). (b) Overview of the direct aspartylation strategy for the synthesis of EPO(78-113) glycopeptide. The dipeptides used in SPPS are underlined. The protected amino acid residues are shown in italic. Reagents and conditions, HATU, DIEA, DMSO.