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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Chem Res Toxicol. 2009 Mar;22(3):574–583. doi: 10.1021/tx8003449

Figure 4.

Figure 4

(a) PAGE analysis of the hOGG1-mediated cleavage products of the substrates containing an 8-oxodG, the two tandem lesions, and unmodified GT. “XY” represents different lesions, and the 20 mer 5′-(CA)-3′- and 5′-(AC)-3′-containing complementary strands were used for the repair studies of the 5′-Tg-(8-oxodG)-3′- and 5′-(8-oxodG)-Tg-3′-containing substrates, respectively. (b) A summary of the quantification results of the percent cleavage products for different substrates. The values represent the mean ± standard deviation from three independent treatments and quantification experiments.