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. Author manuscript; available in PMC: 2010 Mar 27.
Published in final edited form as: J Nat Prod. 2009 Mar 27;72(3):360–365. doi: 10.1021/np800572r

Table 3.

In Vivo Toxicity Data of 1 after 3-day Dosing in Mice

dose (mg/kg) days Rx % survival + comments
300 3 1/5 lethality after 3 days of dosing,
1/5 additional lethality after 3 days of dosing
100 3 transient lethargy after dosing
30 3 no adverse effects