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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Chem Res Toxicol. 2009 Mar;22(3):426–432. doi: 10.1021/tx800315m

Figure 1.

Figure 1

Chromatogram obtained upon LC-ESI-MS/MS-SRM analysis of (A) standard 14a and 14b obtained by the reaction of diol epoxide 11 with N-acetylcysteine. (Mercapturic acids 14c and 14d from syn-11 elute 5 – 8 min later than 14a under these conditions (24)); (B) a 24h incubation mixture of human hepatocytes and 10 µM Phe-3,4-diol (8), and (C) Coinjection of A and B demonstrating an increase in the peak corresponding to 14a. SRM was performed at m/z390 → m/z (209 + 225 + 243 + 261).