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. Author manuscript; available in PMC: 2010 Mar 3.
Published in final edited form as: Biochemistry. 2009 Mar 3;48(8):1663–1674. doi: 10.1021/bi802324w

Figure 7.

Figure 7

Perspective applications of DNA nanotechnology. (a) Assembly of discrete 3D nanoparticle structure to study the inter-paticle plasmonic effect. Shown here is a DNA icosahedron with nanoparticle at each vertex. (b) DNA mediated drug delivery. (c) Small molecule triggered in vivo DNA self-assembly for medical applications. For example, the binding between taken up molecule and an allosteric DNAzyme can trigger the cleavage of the substrate DNA. The released DNA segment can then self-assemble into nanotube, which can be visualized as a pathogen marker or directly lead to cell death. (d) DNA nanochip displaying two aptamers can bring two protein subunits into proximity and therefore induce protein-protein interaction.