Table 1.

Effect of aliskiren on plasma concentration of glucose, free fatty acids, triglycerides and leptin in C57BL/6J mice exposed either to a low-fat (LF) or to a high-fat (HF) diet

	LF		HF
	Vehicle	Aliskiren	Vehicle	Aliskiren
Glucose (mg·L−1)	13.5 ± 0.6	13.7 ± 0.4	14.9 ± 0.3	13.9 ± 0.8
Free fatty acids (mM)	0.39 ± 0.02	0.38 ± 0.01	0.36 ± 0.04	0.34 ± 0.04
Triglycerides (mg·L−1)	5.8 ± 0.4	7.6 ± 0.5*	8.8 ± 0.7≠	7.3 ± 0.3
Leptin (ng·mL−1)	10.4 ± 1.2	6.5 ± 0.9***	13.6 ± 2.0	7.5 ± 0.5***

^*P < 0.05,

^***P < 0.05 saline versus aliskiren,

^≠P < 0.05 (Newman-Keuls's test).