Table 1.
Ca2+ uptake into microsomes
Ca2+uptake (µmol·g−1) | % Inhibition | |
---|---|---|
Microsomes alone | 45 ± 1.0 | NA |
Microsomes + thapsigargin (10−6M) | 13.2 ± 0.6 | 71 |
Microsomes + DPI (3 × 10−5 M) | 36.8 ± 0.7 | 18 |
Microsomes + DPI (10−4 M) | 30.5 ± 0.9 | 32 |
Microsomes from pig coronary artery were incubated for 30 min in the presence of ATP (5 mM), oxalate (5 mM) and blockers (as indicated), and uptake of 45Ca2+ was measured.
Values shown in the table are means ± SEM, from six microsomal preparations.
DPI, diphenyleneiodonium.