Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
SAHA induces a transient increase in acetylated histones in the chromatin associated with the p21WAF1 gene. Chromatin from cells cultured without and with 7.5 μM SAHA for 2 or 24 h was isolated and ChIP assay performed as described above. Gels were scanned and fold induction was determined and graphed for each region indicated of the p21WAF1 gene.
