Figure 4.
Effect of removal of the endothelium of the anterior mesenteric artery on EFS-evoked hyperpolarization in the longitudinal smooth muscle. The endothelium was removed by injecting collagenase (1 mg·mL−1) into the lumen of the artery for 15 min. (A) Typical recordings of EFS-evoked responses in the endothelium-intact (control) or endothelium-removed preparations are shown. (B) Peak amplitudes of EFS-evoked hyperpolarization are summarized as means ± SEM (n= 5). *Significantly different from control values (P < 0.05). EFS, electrical field stimulation.