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. 2009 Oct 30;4(10):e7670. doi: 10.1371/journal.pone.0007670

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) Representative OVCA exhibits predominantly solid tumor growth, with evidence of papillary projections and occasional minute cysts (bar = 25 µm). Inset, higher resolution photomicrograph depicting cuboidal to polygonal pleomorphic microcystic epithelium with anisokaryosis and atypical mitoses of ovarian cancer cell nuclei (bar = 50 µm). (B) OVCA tumor nodule implant on uterine infundibulo-ovarian ligament (arrowhead) adjacent to the ovary (arrow) (bar = 25 µm). Tumor implants occurred throughout the peritoneal cavity, peri-ovarian connective tissues, and invaded surrounding tissues such as intestines, liver and diaphragm. Hematoxylin and eosin (H&E) stained, paraffin-embedded tissue sections.