Skip to main content
. 2009 Nov 2;4(11):e7689. doi: 10.1371/journal.pone.0007689

Table 4. microRNAs and their target biological processes.

Process/Targets microRNA/paralogs
Up regulated in this stroke study Down regulated in this stroke study
Angiogenesis18 miR-19b, -130a, -15a,-16, -222, -320
Hematopoietic regulation5 miR-16, -24, -30c, -106b, -223,
Immune response7 miR-15a, -16, -24, -29a, -93, -181a, -223
Lymphocyte regulation (differentiation & proliferation)7 miR-101, -181a, -16, -24, -22, -103, -30c, let-7c
Cardiac/vascular function20 miR-23a, -23b, -24, -29a, -29c, -30a,-30c, -30d -103, -222 miR-126
Endothelial cell migration, differentiation and survival18 miR-126, -222
Metabolic process regulation6 miR-130a, -29a, -29c, -320
Hypoxia regulation19 miR-23a, -23b, -24, -103, -93, -181a, -15a, -16, -101, -126, -320, let-7c, let-7e, miR-7, let-7a
Traumatic brain Injury (mouse brain)12 miR-103, -130a, -185, -191, -19b, -22, -222, -223, -23a, -23b, -30c, -320, -652, -744
Stroke model (blood of rat-MCAo model)11 let-7c, miR-103, -106b, -16, -185, -191, -19b, -23a, 320, let-7a
Stroke model (brain of rat MCAo model)11,13 let-7c, let-7d*, let-7e, miR-103, -126, -130a, -16, -181a, -185, -191, -222, -223, -23a, -23b, -24, -30c, -324-5p, -320,-29a, -29c, -7 let-7a

The biological processes that are affected by the microRNAs that are differentially expressed in the stroke samples have been analysed. List presented is based on published data.