Table 2.
Genes associated with the GO categories overrepresented in the signature of differentially methylated genes between MDS and normal CD34+ cells
| Accession nos. | Description | |
|---|---|---|
| GO:0007416 Synaptogenesis | ||
| NRCAM | NM_001037133/NM_005010/NM_001037132 | Neuronal cell adhesion molecule isoforms C, B, and A |
| PCDHB10 | NM_018930 | Protocadherin β 10 precursor |
| PCDHB16 | NM_020957 | Protocadherin β 16 precursor |
| PCDHB9 | NM_019119 | Protocadherin β 9 precursor |
| GO:0043406 Positive regulation of MAP kinase activity | ||
| ADRB2 | NM_000024 | Adrenergic, β-2-, receptor, surface |
| CXCR4 | NM_001008540/NM_003467 | Chemokine (C-X-C motif) receptor 4 isoforms a and b |
| MADD | NM_003682/NM_130471/NM_130472/NM_130474/NM_130470/NM_130473/NM_130475/NM_130476/NM_001135943/NM_001135944 | MAP-kinase activating death domain-containing |
| MAP3K5 | NM_005923 | Mitogen-activated protein kinase kinase kinase |
| PAK1 | NM_002576/NM_001128620 | p21-Activated kinase 1 isoforms 1 and 2 |
| PROK2 | NM_021935/NM_001126128 | Prokineticin 2 isoforms a and b precursor |
| TNF | NM_000594 | Tumor necrosis factor α |
| GO:0000187 Activation of MAPK activity | ||
| ADRB2 | NM_000024 | Adrenergic, β-2-, receptor, surface |
| CXCR4 | NM_001008540/NM_003467 | Chemokine (C-X-C motif) receptor 4 isoforms a and b |
| MADD | NM_003682/NM_130471/NM_130472/NM_130474/NM_130470/NM_130473/NM_130475/NM_130476/NM_001135943/NM_001135944 | MAP-kinase activating death domain-containing |
| MAP3K5 | NM_005923 | Mitogen-activated protein kinase kinase kinase |
| PROK2 | NM_021935/NM_001126128 | Prokineticin 2 isoforms a and b precursor |
| TNF | NM_000594 | Tumor necrosis factor α |