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. 2009 Oct;50(5):455–464. doi: 10.3325/cmj.2009.50.455

Figure 3.

Figure 3

Receiver operator characteristic (ROC) curves of high-mobility group box-1 (HMGB1), squamous cell carcinoma antigen (SCCA antigen), cytokeratin fragment 21-1 (CYFRA21-1), and carcinoembryonic antigen (CEA) in patients with recurrent cervical SCCA. The clinical relevance of HMGB1, SCCA antigen, CYFRA21-1, and CEA was compared by establishing ROC curves. The ROC curves of HMGB1 and SCCA antigen were located closer to the theoretical 100% sensitivity and specificity values than the ROC curves of other investigated markers.