Skip to main content
. Author manuscript; available in PMC: 2010 Oct 8.
Published in final edited form as: J Med Chem. 2009 Oct 8;52(19):5950–5966. doi: 10.1021/jm900496b

Figure 5. Evaluation of Bexarotene (Compound 1) and selected analogs for apoptotic activity utilizing a Caspase 3/7 assay in CTCL cells.

Figure 5

Human T-cell lymphoma cells (CTCL) were plated and immediately dosed with the indicated treatments. Cells were allowed to incubate for 24 hours and the level of apoptosis was measured with a commercial kit (see Experimental Section). Sodium butyrate (Na Bu), a known inducer of apoptosis, was used as a positive control.