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. Author manuscript; available in PMC: 2010 Oct 29.
Published in final edited form as: J Phys Chem B. 2009 Oct 29;113(43):14329–14335. doi: 10.1021/jp904830m

Figure 6.

Figure 6

Binding isotherms of netropsin to three DNA hairpins. The primary binding affinity to a short 8-base-pair stem with a TCTC loop (5′CGAATTCGTCTCCGAATTCG-3′ or 8bp_TCTC) is lower than that of a 10-base-pair stem with the same loop (5′GCGAATTCGCTCTCGCGAATTCGC-3′ or 10bp_TCTC) or a 10-base-pair stem with a hexa-ethylene glycol loop (5′GCGAATTCGCPO3(C2H4O)6GCGAATTCGC-3′ or 10bp_6-EG).