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. 2009 Jun 6;28(4):410–417. doi: 10.1007/s11239-009-0354-y

Table 3.

Change in the levels of (A) sCD40L, (B) P-selectin and (C) hsCRP over 4 weeks presented as medians and interquartile ranges as well as mean percentage change

Baseline Week 1 Week 2 Week 3 Week 4
(A) sCD40L levels over 4 weeks after clopidogrel cessation
CD40L
    Median 224 298 285.5 292 324.5
    Max 1450 2483 2559 2871 2474
    Min 10 36 23 42 18
    Q3 364.5 478 569.5 509 541
    Q1 129.5 161 160.75 155 199.5
    Upper limit of normal 0 pg/ml
    Lower limit of normal 5000 pg/nl
    Average 310.2 434.9 469.1 412.9 446.1
    Std 282.3 453.8 483.7 431.3 409.5
    Mean percent change from baseline + SE 35% + 10% 39% + 11% 33% + 10% 39% + 11%
P < 0.001 P < 0.001 P < 0.001 P < 0.001
(B) P-selectin levels over 4 weeks after clopidogrel cessation
P-selectin
    Median 44 49 50 45.5 45
    Max 104 114 138 147 150
    Min 20 22 9 17 23
    Q3 58 60.25 60.25 59 55.25
    Q1 37 40 39 35 35
    Upper limit of normal 51 ng/ml
    Lower limit of normal 113 ng/ml
    Mean 47.2 51.3 51.7 49.2 48.1
    Std 16.2 17.2 18.7 20.1 20.3
    Mean percent change from baseline + SE 9% + 2% 11% + 2% 4% + 3% 2% + 3%
P < 0.001 P < 0.001 P = 0.173 P = 0.488
(C) Levels of CRP over 4 weeks after clopidogrel cessation
hsCRP (mg/L)
    Median 1.59 1.25 1.1 1.11 1.22
    Min 0.1 0.1 0.2 0.2 0.1
    Max 57.9 27.7 15.6 62.9 19.5
    Q3 3.70 2.61 3.46 3.29 2.83
    Q1 0.74 0.72 0.66 0.62 0.61
    Average 3.92 2.39 2.33 2.87 2.76
    Std 7.73 3.60 2.63 6.70 3.96
    Lower limit of normal 0 mg/L
    Upper limit of normal 11 mg/L
    Mean percent change from baseline + SE −21% + 7% −23% + 7% −19.% + 8% −18% + 8%
P = 0.008 P = 0.004 P = 0.038 P = 0.062