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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Pharmacol Biochem Behav. 2009 Sep 17;94(2):296–304. doi: 10.1016/j.pbb.2009.09.009

Figure 2.

Figure 2

Predicted center distance travelled in male and female periadolescent rats following repeated saline (SAL) or lobeline (LOB; 1.0–10 mg/kg) injection. Rats exhibited tolerance to the repeated effects of LOB and females developed tolerance to repeated LOB 5.6 mg/kg at a slower rate than males (p<0.01). n = 10–12 animals/group.