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Effect of famotidine on ghrelin-stimulated acid output in gastric lumen-perfused rats. Time course of acid output by the IV administration of famotidine (0.33 mg/kg) and ghrelin (20 μg/kg) in gastric lumen-perfused rats. Famotidine was administered intravenously 15 min before ghrelin injection. Each value represents the mean ± SE of acid output at 15 min intervals. n = 4. Reprinted with permission[30].
